PATTERNS OF STRUCTURAL ORGANIZATION OF THE BRONCHOPULMONARY SYSTEM IN CLINICALLY HEALTHY WHITE OUTBRED RATS
PDF

Keywords

bronchopulmonary system; morphometry; rats; lung histology; tissue remodeling; baseline values

How to Cite

Zharlykassynova , G., & Boltaeva , Z. (2026). PATTERNS OF STRUCTURAL ORGANIZATION OF THE BRONCHOPULMONARY SYSTEM IN CLINICALLY HEALTHY WHITE OUTBRED RATS. WORLD INTERNATIONAL CONFERENCE ON SCIENCE, TECHNOLOGY AND EDUCATION, 1(4), 190-192. https://doi.org/10.5281/zenodo.19712804

Abstract

The study evaluates the structural and morphometric features of the bronchopulmonary system in clinically healthy white outbred rats to establish reference parameters. Thirty rats (6, 9, and 12 months) were examined using histological and morphometric methods. An age-dependent increase in bronchial epithelium height, basement membrane thickness, and interalveolar septa was identified, most pronounced in 12-month-old animals. The findings reflect physiological tissue maturation without pathological changes. The obtained data can serve as baseline values for experimental studies of respiratory pathology.

PDF

References

1. Pashinyan G.A., Sorokina O.A. Morphological and morphometric characteristics of the bronchi in laboratory rats. // Bulletin of Human Morphology. - 2020. - Vol. 26, No. 1. - P. 81–88.

2. Nuraliyev N.A., Bektimirov A.M., Alimova M.G., Suvanov K.Zh. Rules and methods of working with laboratory animals in microbiological and immunological studies. - Method. manual. - Tashkent: Ministry of Health of the Republic of Uzbekistan, 2016. - 42 p.

3. World Health Organization. Global report on trends in prevalence of tobacco smoking 2000–2025. — 4th ed. — Geneva: WHO, 2021. — 128 p.