Vol. 1 No. 10 (2026), Articles
Vol. 1 No. 10 (2026)

EFFECTS OF SALVIA OFFICINALIS L. AND PUNICA GRANATUM L. PEEL EXTRACTS ON ERYTHROCYTE INTEGRITY IN RATS WITH TYPE 2 DIABETES MELLITUS

Articles
Published 2026-10-13
Ozoda Khamidova
Institute of Biophysics and Biochemistry, National University of Uzbekistan, Tashkent 100174, Uzbekistan
Ranokhon Kurbannazarova
Department of Exact and Natural Sciences, Kattakurgan State Pedagogical Institute, Kattakurgan, Uzbekistan
Ravshan Sabirov
Department of Exact and Natural Sciences, Kattakurgan State Pedagogical Institute, Kattakurgan, Uzbekistan
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Keywords

T2DM, erythrocytes, hemolysis, Salvia officinalis L., Punica granatum L.

How to Cite

Ozoda Khamidova, Ranokhon Kurbannazarova, & Ravshan Sabirov. (2026). EFFECTS OF SALVIA OFFICINALIS L. AND PUNICA GRANATUM L. PEEL EXTRACTS ON ERYTHROCYTE INTEGRITY IN RATS WITH TYPE 2 DIABETES MELLITUS. WORLD INTERNATIONAL CONFERENCE ON SCIENCE, TECHNOLOGY AND EDUCATION, 1(10), 158-160. https://doi.org/10.5281/zenodo.23330816
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Abstract

This thesis evaluates changes in erythrocyte hypoosmotic and nystatin-induced colloid-osmotic resistance in experimental type 2 diabetes mellitus and the corrective effects of sage and pomegranate peel extracts. The results showed that pomegranate peel was more effective in correcting colloid-osmotic resistance, whereas sage produced a stronger glucose-lowering effect.

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References

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2. Furman BL. Streptozotocin-induced diabetic models in mice and rats. Curr Protoc. 2021;1(4): e78. doi: 10.1002/cpz1.78.

3. Khamidova O.J., Oljaev N.D., Fayziev D.D., Merzlyak P.G., Kurbannazarova R.Sh., Maksudov M.Z., Sabirov R.Z., Abdullaev I.F. (2026) Erythrocyte integrity, thymocyte volume regulation, and functional state of the heart during ischemia/reperfusion in rats with type 2 diabetes mellitus. Bull. Exp. Biol. Med. 180(3):307-311. doi: 10.1007/s10517-026-06626-9.