Keywords
How to Cite
Abstract
Metabolic-associated steatotic liver disease is currently one of the most pressing issues in hepatology and metabolic medicine. In addition to insulin resistance, obesity, dyslipidemia, and chronic low-grade inflammation, hormonal imbalance and genetic factors also play a significant role in the development of this disease. In particular, in women of reproductive age, special importance is attributed to estrogens, androgens, sex hormone-binding globulin, the aromatase system, as well as genes associated with steroid metabolism.
References
1. Tacke F. va hammualliflar. EASL–EASD–EASO Clinical Practice Guidelines on the management of metabolic dysfunction-associated steatotic liver disease. Journal of Hepatology. 2024.
2. Jancova P. va hammualliflar. Relationship between MASLD and women’s health: A review. 2025.
3. Weiskirchen R. va hammualliflar. Sex Hormones and Metabolic Dysfunction-Associated Steatotic Liver Disease. 2025.
4. Di Stasi V. va hammualliflar. SHBG as a marker of NAFLD and metabolic impairments in women with PCOS. 2021.
5. Xing C. va hammualliflar. The Association of CYP19A1 and SHBG Gene Polymorphisms in PCOS Susceptibility. 2022.