Abstract
The aim of the study was to evaluate the diagnostic value of serum cystatin C for early renal risk stratification in patients with prediabetes. The study included 55 patients with carbohydrate metabolism disorders and 20 healthy individuals. A significant increase in cystatin C, C-reactive protein, and lipid profile parameters was observed in prediabetic patients compared to controls (p<0.005), while creatinine levels remained within normal limits. Elevated cystatin C was associated with early signs of renal dysfunction. These findings support the use of cystatin C as a sensitive biomarker for detecting subclinical kidney damage in patients with prediabetes.
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