Abstract
The clinical and functional characteristics of the symptom complex and systemic hemodynamic parameters were investigated in 120 patients with ischemic heart disease combined with arterial hypertension. A predominance of anginal syndrome and dyspnea was identified, along with a high frequency of asthenic manifestations. More than 46% of patients experienced frequent angina attacks accompanied by pronounced hemodynamic disturbances. Gender- and age-related features were also observed, including a more pronounced clinical manifestation in middle-aged women.
References
1. Apple F.S. et al. High-sensitivity cardiac troponin assays: clinical update from the Academy of the American Association for Clinical Chemistry. // Clin Chem. – 2017. – V. 63(1). – P. 73–81.
2. Bernatsky S, Lewin A, Usmanov RS. Ситуация и прогнозирование ИБС и АГ в Узбекистане. // J Cardioprophylaxis Uzbekistan. – 2020. – V. 5(2). – P. 12–20.
3. Caylı M. et al. High‑sensitivity cardiac troponin T predicts nondipper hypertension in newly diagnosed hypertensive patients. // J Clin Hypertens. – 2013. – V. 15(10). – P. 731–737.
4. de Lemos J.A. et al. Association of troponin T levels with cardiac structure, mortality risk, and myocardial ischemia in the general population. // JAMA. – 2010. – V. 304(22). – P. 2503–2512.
5. Everett B.M. et al. High‑sensitivity cardiac troponin I and B‑type natriuretic peptide as predictors of vascular events in primary prevention: impact of statin therapy. // Circulation. – 2015. – V. 131(10). – P. 863–872.