EFFECTIVENESS OF DETOXIFICATION THERAPY IN CHRONIC NICOTINE INTOXICATION OF THE BRONCHOPULMONARY SYSTEM

Abstract

Chronic nicotine intoxication leads to pronounced structural alterations in the bronchopulmonary system, including inflammation and fibrosis. In an experimental study involving 120 rats, the effectiveness of detoxification therapy using Mumiyo and a biologically active supplement was evaluated. It was established that both therapeutic approaches contribute to the restoration of lung tissue architectonics, reduction of inflammatory processes, and attenuation of fibrotic changes. Notably, Mumiyo demonstrated greater efficacy in restoring epithelial structures, whereas the biologically active supplement exhibited pronounced antifibrotic and angioprotective properties.