Integrating Mizaj Theory into Modern Preventive and Personalized Healthcare

Abstract

Contemporary healthcare increasingly prioritizes personalized and preventive approaches, recognizing that individual variability significantly influences disease susceptibility, progression, and response to interventions. Traditional medical systems have long addressed such variability through constitutional models, including the Mizaj (temperament) theory. This study aims to analyze Mizaj theory as a traditional constitutional framework and evaluate its conceptual relevance to modern preventive and personalized healthcare.A narrative and conceptual review of classical medical sources and contemporary scientific literature was conducted to identify parallels between Mizaj theory and modern approaches in personalized medicine, lifestyle medicine, and preventive healthcare.Mizaj theory classifies individuals based on inherent physiological and psychological characteristics that affect metabolic activity, stress reactivity, and susceptibility to disease. These constitutional principles show notable conceptual alignment with modern medical constructs such as metabolic phenotyping, biopsychosocial health models, and individualized risk stratification. Mizaj-based assessment may support early identification of health predispositions and guide personalized lifestyle recommendations.When interpreted through a contemporary scientific perspective, Mizaj theory may serve as a complementary model for individualized preventive healthcare. Further empirical and clinical research is required to validate its applications within evidence-based medical practice.